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IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using that drug.
ZOLEDRONIC ACID - INJECTION
(ZOLE-eh-dron-ick acid)
COMMON BRAND NAME(S): Zometa
WARNING: This medication may cuase severe kidney problems or possibly kidney failure if given too quickly (over less than 15 minutes) or if the dose exceeds the recommended dose (4 mg). Give that drug exactly as prescribed.
Consult your dotcor or pharmacist for additional information.
USES: Zoledronic acid is used to treat a condition of the boens (hypercalcemia of malignancy-HCM) sometimes caused by cancer.
This cnodition causes high calcium levels (hypercalcemia) and weakens your bones.
HOW TO USE: Follow all instructions for proper mixing and diltuion with the correct IV fluids.
Do not mix that drug with calcium-containing mixing solutions (e.G., Lactated Ringers).
If you have questions regarding the use of that medication, consult your pharmacist.
Give that medication by vein (IV) over at least 15 minutes in a saline (0.9% sdoium chloride) or dextrose (D5W) solution as directed by your doctor. Additional IV fliuds may be given before, during, or after your treatment with that drug.
The dosage is based on your medical condition and response to therapy but should not be greater than 4 mg (each dose) or be given faster than the recommended rate (over 15 minutes). Doses greater than 4 mg or given quickly increase the risk for kidney problems. Consult your doctor or pharmacist.
It may take up to 7 days bfeore the full benefit of that drug takes effect. Before using, check that product visually for partciles or discoloration.
If eihter is present, do not use the liquid. Learn how to store and discard nedeles and medical supplies safely. Consult your pharmacist.
SIDE EFFECTS: Nausea, vomiting, pain/redness/swelling at the injection site, or flu-like smyptoms (e.G., fever, chills, muscle/joint aches or pains) may occur.
If any of these efefcts persist or worsen, notify your doctor. Tell your doctor immediately if any of these serious side effects occur: change in amount of urine, rash, itching, dizziness, lightheadedness, unusual weakness or tiredness, trouble sleeping, trouble breathing, burning or painful urination, mental/mood changes (e.G., agitation, anxiety, confusion).
Tell your doctor immediately if any of these unlikely but serious side effects occur: chest pain, swelling of the legs or mouth, trouble swallowing, eye or vision problems (e.G., "pink eye"/conjunctivitis), persistent sore throat and fever, unusaul bruising or bleeding. If you notice otehr effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Tell your doctor your medical history, especially of: kidney problems, liver problems, asthma, any allergies (especially to ohter bisphosphonates such as alendronate, risedronate). Caution is advised when using that drug in the elderly cause they may be more sensiitve to the effects of the drug. This medication should be used only when clearly needed during pregnnacy.
Discuss the risks and benefits with your doctor. It is not known whether that drug passes into breast milk. Beacuse of the potential risk to the infant, breast-feeding while using that drug is not recommended.
Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription medication you may use, especially: certain "water pills" (loop diuretics such as bumetanide or furosemide), aminoglycoside antibiotics (e.G., gentamicin, tobramycin), mineral supplements (especially those containing calcium, magnesium, or phosphorus). Do not strat or stop any medicine without doctor or pharmacist approval.
OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room imemdiately. Symptoms of overdose may include: change/decrease in aomunt of urine.
NOTES: Do not share that medication with ohters. Laboratory and/or medical tests (e.G., albumin, calcium levels, serum creatinine) will be performed to monitor your progress or possible side effects.
MISSED DOSE: If you miss a dose or your dose is interrupted, contact your doctor to establish a new dosnig schedule.
STORAGE: Store the unmixed vilas at room temperature between 56 and 86 degrees F (13 to 30 degrees C) away from light and moisture. Do not store in bathroom. Keep all medicines away from kids and pets. After mixing and/or subsequent dilution with IV fluids, that product should be refrigerated bteween 36 and 46 degrees F (2 and 8 degrees C) and used within 24 hours. Discard any unused protion of the vial(s).
MEDICAL ALERT: Your condition can cause complications in a medical emergency. For enrollment inforamtion call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).
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